Name: Chicken and Stuffing Casserole
Prep time: 10 min
Cook time: PT-488376H56M15S
Total time: PT-488376H56M15S
Cuisine: American
Ingredients: Boneless, skinless chicken breasts or thighs (cooked and shredded, or raw if baking longer); Cream of chicken soup (or cream of mushroom, cream of celery, or homemade substitute); Sour cream; Chicken broth; Boxed stuffing mix (like Stove Top, or homemade); Butter, melted; Optional vegetables: frozen peas, green beans, or mixed veggies

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This chicken and stuffing casserole is one of my favorite cozy, all-in-one meals. Tender chicken is baked under a layer of creamy sauce and topped with golden, buttery stuffing. It’s simple, hearty, and the kind of comfort food I love making on busy weeknights or chilly weekends.

Why You’ll Love This Recipe

I love this casserole because it feels like Thanksgiving in a pan—but it’s easy enough for a regular weeknight. The chicken stays juicy, the creamy sauce ties everything together, and the stuffing topping bakes up crispy on the edges and soft underneath. It’s also versatile—I can throw in vegetables or use leftover rotisserie chicken, making it a reliable dinner option. Chicken and Stuffing Casserole

Ingredients

(Here’s a tip: Check out the full list of ingredients and measurements in the recipe card below.)

Boneless, skinless chicken breasts or thighs (cooked and shredded, or raw if baking longer)
Cream of chicken soup (or cream of mushroom, cream of celery, or homemade substitute)
Sour cream (for extra creaminess)
Chicken broth (to moisten the stuffing)
Boxed stuffing mix (like Stove Top, or homemade)
Butter, melted
Optional vegetables: frozen peas, green beans, or mixed veggies

Directions

Prep the chicken:
I cook and shred chicken ahead of time, or cube it if I want chunkier bites. (If I use raw chicken, I bake the casserole longer until fully cooked through.)
Mix the sauce:
In a bowl, I stir together cream of chicken soup and sour cream. This makes a creamy layer to keep the chicken moist.
Assemble the casserole:
In a greased baking dish, I spread the chicken evenly, then pour the soup mixture over the top.
Add stuffing:
I prepare the stuffing mix by combining it with melted butter and a little chicken broth, then spread it evenly over the casserole.
Bake:
I bake uncovered at 350°F (175°C) for 30–40 minutes, until the casserole is bubbling and the stuffing is golden brown.
Serve:
I let it cool for a few minutes, then scoop and serve warm.

Servings and Timing

This recipe serves 6 people.
Prep time: 10 minutes
Cook time: 30–40 minutes
Total time: 40–50 minutes

Variations

I sometimes stir in vegetables (like green beans, corn, or peas) for a complete one-pan meal.
Using leftover turkey instead of chicken makes this a great post-holiday recipe.
For a cheesier version, I sprinkle shredded cheddar or mozzarella under the stuffing layer.
I swap sour cream with Greek yogurt for a lighter option.

Storage/Reheating

I store leftovers covered in the fridge for up to 3 days.
To reheat, I bake in the oven at 350°F until warmed through, or microwave individual portions.
This casserole also freezes well—up to 2 months. I thaw it in the fridge overnight and reheat in the oven.

FAQs

Can I make this casserole ahead of time?

Yes—I assemble everything, cover, and refrigerate up to 24 hours in advance. I just bake it when ready to serve.

Do I need to cook the chicken first?

Not always. If I use raw chicken, I bake closer to 45–50 minutes and make sure the chicken reaches 165°F internally.

Can I use homemade stuffing?

Definitely. I sometimes use leftover bread cubes with broth, butter, and seasonings instead of boxed stuffing.

How do I keep the stuffing from getting soggy?

I use less broth when preparing the stuffing if I want it crispier, and I bake uncovered so the top browns nicely.

What can I serve with this casserole?

It’s hearty enough on its own, but I like pairing it with a simple green salad, roasted vegetables, or cranberry sauce for a holiday-style touch.

Conclusion

This chicken and stuffing casserole is pure comfort food—creamy, savory, and topped with that irresistible buttery stuffing crust. It’s quick to make, versatile with add-ins, and perfect for feeding a hungry family. Whenever I’m craving something cozy and filling, this casserole always hits the spot.